I invite you to take a look at this forum post from 'Benys'
It illustrates the power of the Entity Framework's mapping capabilities + partial classes.
The short answer to a lot of "Does the EF support ... ?" type questions is often no.
Often however the longer answer, is a little easier to digest.
If you start using the power of DefiningQueries / Partial Classes / View / Stored Procs suddenly lots of things become possible.
The nice thing about 'Benys' example is that while UDTs ( spatial types are basically UDTs ) are not natively supported by the Entity Framework, there is a nice work around...
Here is the pattern:
The are a few caveats of course*, but this is just the sort of work-around that allows you to handle an issue that might otherwise be a real show-stopper.
* Issues (non exhaustive list)