http://blogs.msdn.com/b/asiatech/archive/2013/02/19/wcf-msmq-intermittent-mq-error-transaction-sequence-error.aspxMy customer has an application runs fine until upgraded to WCF 4.0. After that, he received follow message intermittently. 0xc00e0051 means MQ_ERROR_TRANSACTION_SEQUENCE. &lt;Message&gt; An error occurred while receiving a message from the queueen-USTelligent Evolution Platform Developer Build (Build: 5.6.50428.7875)http://blogs.msdn.com/b/asiatech/archive/2013/02/19/wcf-msmq-intermittent-mq-error-transaction-sequence-error.aspx#10396088Fri, 22 Feb 2013 01:10:43 GMT91d46819-8472-40ad-a661-2c78acb4018c:10396088alabax<p>Nice article, I recently came across the same issue. However the statement: &quot;WCF allows only making the transaction timeout smaller than the default System.Transactions timeout (1 minute).&quot; is not true. ServiceTimeoutsElement.TransactionTimeout can be effectively greater than DefaultSettingsSection.Timeout but not greater than MachineSettingsSection.MaxTimeout. So by default effective transactionTimeout value is limited by 10 minutes.</p> <div style="clear:both;"></div><img src="http://blogs.msdn.com/aggbug.aspx?PostID=10396088" width="1" height="1">