Krzysztof Cwalina and I had a chance to sit down and chat with informIT just On_Microsoft before the PDC to talk about how the design guidelines have evolved over the last 10 years.    The latest version of the guidelines have just been published as the Framework Design Guidelines 2nd Edition

10 Years of Framework Design Guidelines (video)

Also, Krzysztof and I did an interview where we talked about what is new with the Framework Design Guidelines 2nd Edition

Framework Design Guidelines: Conventions, Idioms, and Patterns for Reusable .NET Libraries (video)