The last post I indicated none of the applications were happy as they were now all sitting on the wrong drive letter
I eventaully remapped the drive letters but this wasn't easy as easy as right click on the drives in the MMC and rename due to the fact it was the boot volume(which you are not allowed to change).
That said there is an article that describes how to do this: http://support.microsoft.com/default.aspx?scid=kb;EN-US;Q223188 through some scary registery keys.
After remapping the drive and restarting the computer got stuck in a continual reboot loop with an error "Object Not Found" from LSASS.EXE - the problem here was the page file had bad pointers to the old drive letter. I was able fix this by making some change to the page file ( I changed the size)
I think I FINALLY have it working!!