We've seen some people reporting issues on VS2010 RC setup UI disappearing or giving an error after clicking Next on Welcome page or Options page. If you are experiencing this issue, please check out http://social.msdn.microsoft.com/Forums/en-US/setupprerelease/thread/dbcdcd52-d162-4460-9920-33c9ab54b36f which may help you workaround the problem.

This issue has been mostly manifesting on Windows XP SP3 systems with handwriting recognition enabled. If you are experiencing this issue under other system configuration, please leave us a comment, we are investigating on the problem.

Thanks!