FunScript is “a lightweight F# library that lets you rapidly develop single-page web and mobile applications”.
This now has a nice new home page: http://funscript.info/
It is interesting because:
Some nice samples:
Charting WorldBank Data (code)
Calling the Movie Database (code)
If you’re interested in using one language on JS client and .NET server it may be worth a look for single page apps. Another excellent alternative is WebSharper.