Please notice that the Infrastructure Update KB has been updated to include the following: 

   Known issues discovered after release of this update

   Installing the Infrastructure Update in a SharePoint farm that uses Alternate Access Mapping with a
   reverse proxy or a network load balancer, such as in an extranet deployment, may cause some
   public URLs to become unresponsive.

   Microsoft is aware of this issue and is developing a solution. Before installing the Infrastructure Update,
   customers who use this configuration should use a test environment to verify that public URLs remain
   accessible after the update is installed.