If you're looking for MSDN documentation on the Visual Studio 2005 Profiler, here's the main starting point:

http://msdn2.microsoft.com/en-gb/library/z9z62c29(VS.80).aspx

I just realized this page doesn't actually have the word "profiler" anywhere on it, making it really hard to find for people searching on the "profiler" keyword. 

PS: This is not entirely an attempt to manipulate weak minded search bots. I've actually had real people ask me this!