Paul Stubbs blogs about how easy we made deployment in VSTO Orcas.
We got rid of our dependency on caspol and now have a version independent policy store. We now use ClickOnce including the ClickOnce cache. We do automatic update checking on an interval specified by the developer so you can publish your add-in to the web and users can get updates automatically. We support web site, UNC shares, or CD/removable storage installs
In short, I think we really made deploying VSTO document and add-in solutions for Office 2007 easy.