Catching up on my reading when I saw this provocative question...

Who wouldn’t want to participate in a world of reduced cost, increased agility, higher performance and quicker response to ever-changing business needs?
http://www.windowsfs.com/tabid/54/articleType/ArticleView/articleId/832/Default.aspx

The article was about mainframe migration - a key cost consideration in several industries including Financial Services and Health & Life Sciences. If you are looking for resources on migrating, please visit the Mainframe Migration Alliance for additional case studies, videos, presentations and whitepapers, in addition to the Mainframe Modernization page on Microsoft.com.

This was timely information as I tried to relate this to some recent content around BizTalk Server 2006 R2:

BizTalk Server 2006 R2 Legacy Modernization with Host Integration Server 2006: This poster provide a high level view of the Legacy Modernization Scenarios that are made possible using BizTalk Server 2006 R2 Adapters for Host Systems and Host Integration Server 2006. It also include detailed architecture diagrams to illustrate specific integration and interoperability scenarios between Windows servers and solutions and IBM mainframe and midrange resources.

P.S. If you like this poster, there are many other BizTalk Server posters around run time architecture, product capabilities and scale out configuration. Follow the links here. Don't forget, you can always try out a virtual lab on BizTalk Server 2006 R2 in the cloud!