I really like reading ReadWriteWeb... one of the best sources I found on Web 2.0 and the Progamable Web. Richard MacManus was kind enough to post his real-time notes from O'Reilly's keynote from the Web 2.0 expo. We learned about the big opportunities:

1) web 2.0 in enterprise; "turning themselves inside out"
2) web 2.0 evolving into cloud computing
3) ambient computing (mobile phones and ubiquitous sensors)

No. 1) Web 2.0 in the enterprise: "turning themselves inside out" is something really changing the game. Traditionally companies paid expensive PR and marketing firms to "Manage the Brand" and would not ever consider letting unfiltered, unmanaged messages escape into the the ether. However, companies embracing web 2.0 technologies have this side effect of becoming more transparent to the world. Take GM FastLaneBlogs were we hear directly from Robert Lutz on GM in a more person to person exchange that is the blog experience.

Here we see Bob being quite candid on wrong strategy decisions when considering Hybrid technologies. Here is a quote: (Volt is GM's Prius)
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I told the Volt Nation audience that GM had the technology to do hybrids back when Toyota was launching the first Prius, but we opted not to ask the Board to approve a product program that’d be destined to lose hundreds of millions of dollars. In the end, it cost us much more than that; it cost us our reputation for technology leadership and innovation.
>>
Quite true considering how we learned today that Toyota top GM as the world's top auto Seller
This post generated tons of comments from all ilk. A lot of GM lovers and haters chimed in... including one comment from progressive insurance actually providing good advice on how GM could improve its green image. Web 2.0's side effect of "Opening the Kimono" has benefits. Good Intellectual Properity can be contributed to your interest without a lot of effort.

Opening TopWeb (vs.TopDown) communication channels is one way the Enterprise is "turning themselves inside out". The other way is BottomWeb (vs. BottomUP). Microsoft has embraced this concept with allowing any Full Time Employee to be able to create a blog (like this one). Employees are given blogging guidance but in general we have the good freedom on blogging topics using our best judgement on what we write. This BottomWeb Enterprise Transparency has done a great service in helping Microsoft and the world communicate with each other.  A good is example is ScottGu's second blog post, Hitting Code Complete, from Feb 16, 2003 which we learned some good tidbits into Microsoft's development process which at the time we learned needed some attention on the security with SQL Slammer hitting the month before. (Scott's IIS 6 has been a very  secure web server considering only 5 secunia advisories were issued.)

ScottGu's blog has become one of the most popular viewed blogs at Microsoft because of his releasing the latest info on web development and quality of his posts. His posts are returning on the top of search results for the latest how to's on web progamming.. ahead of traditional published developer content like "official" msdn documetation. This sharing of information about a company and company products at the indvidual employee level  is the way of the future.