This tip was posted a long time ago on my blog, but I thought it would be a good one to start with anyway. :)
Manage your breakpoints via a group names. If I have time, I will eventually modify these macros to support the notion of labels (the idea of grouping single bp's by more than one name), rather than having a one-to-one association of bp to name. Or if you feel particularly energetic you could try that yourself!