Lang.Net 2008 is coming up this Monday through wed (Jan 28th -Jan 30th). This is targeted at compiler and language implementers. The agenda is here and includes a lot of great Microsoft and non-Microsoft folks. In my former debugging life, my angle for these sort of conferences was from the debugger perspective. (Here were my takes on the Compiler Labs last May '07 and Feb '05) This will be the first time I'll be at a language conference as a non-debugger guy. I suspect it will feel strange.
Jimmi Schementi has got more to say about it here. (He also wrote a good DLR article on Msdn)