Code Access Security (CAS) can be a difficult concept for developers to wrap their heads around, so I imagine that for non-developers CAS is probably a complete mind twist. There’s a set of whitepapers at http://www.combined-knowledge.com/Downloads%202007.htm that describe various tasks, mostly focusing on the admin side of things. Within that list of whitepapers, there’s a really good description of Code Access Security in SharePoint for Administrators that talks about the different CAS security levels, why you should not run your site using the “Full” trust level, and demonstrates how to create a custom policy for your assemblies.
Should be a required read for anyone tempted to ask their SharePoint administrator to run the farm using Full trust.
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