Hot off the press! IronPython RC1 has been released. If you haven't played with it yet, you really should.

IronPython 1.0 is supposed to be compatible with CPython 2.4, so if you have any CPython 2.4 application, you should be able to port it to IronPython with minimum re-work.

http://www.codeplex.com/Wiki/View.aspx?ProjectName=IronPython

Let me know how it go for you! :)