As you might know running PHP applications on Windows Server 2008 (and Vista SP1) and Internet Information Services 7 (IIS7) is supported through the FastCGI module. If you need to learn more there is good news: a full training kit has been released. Besides addressing configuration of PHP on IIS 7 it also contains demos and labs on how to take advantage of SQL Server from PHP applications.
PHP & SQL Server Demos
Download “PHP on Windows Training Kit (April 2009 update)”
PingBack from http://asp-net-hosting.simplynetdev.com/php-on-windows-training-kit-available-april-2009-update/
I had a lot of trouble getting PHP to work with IIS 6.0 on my 2003 Server. I hate to say this but I installed Apache and it runs smoothly now - :)
The support for PHP applications is much better in IIS7 (with FastCGI), so maybe you should give it a try now with Windows Server 2008 ;-)