There is a ton of data on how to and what it will take... Simon has posted the link to a great webinar that tells you about the "rest" of the Microsoft stack and how hosting works with it. Are you planning on hosting? If so, let me know so we can start working out some of these details with you and the hosting team.

http://blogs.msdn.com/ukcrm/archive/2005/12/16/504866.aspx