I see that Don Box is getting some pushback  from various folks on his post on Pragmatics.  Maybe this will make it a bit clearer :-)

The following equipment purchase decisions are orthogonal, even though people often conflate two or more of them:

1. Whether one uses big trucks or economy cars
2. Whether or not one prefers to buy from American or European/Asian manufacturers.
3. Whether or not one buys fuel at retail or enters long-term wholesale contracts.
4. The degree to which one relies on the specific details of a particular truck or car to make long term planning decisions.
5. Whether one adopts a hub and spoke or point to point distribution network

Some of the decisions (specifically 5) are architectural and sometimes philosophical.

Some of the decisions are simple business decisions that are determined by what your business is.

1. If you want to haul a lot of heavy stuff securely and reliably, use a truck
2. If you want a to move people or light objects around quickly and cheaply, use an economy car.
3. If you want to do both, buy both trucks and economy cars
4. If you want to make money, you will not listen to dudes who think diesel trucks are the only macho way to get around, or to environmental geeks who think they are evil because they smell bad.