OK, so I'm really excited about CRM 'Titan' and I'm actively recruiting UK ISVs onto our early adopter 'Ascend' program.
The multi-tenanted, multi-lingual and multi-currency features are fantastic and will definitely open up a host of opportunities. There are even more features, particularly from an ISV point of view, which will lead to greater architectural opportunities and improvements, however...
Whilst I can't go into all of the features yet (although do watch this space!) there is an article here which talks about our recent announcement.