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The advent of electronic medical records is transforming the care of patients in hospitals, clinics, and doctors’ offices around the world. Offering complete documentation of a patient’s medical history, digitized records are improving the accuracy of diagnoses and the continuity of patient care, which, in turn, means improved patient outcomes.
Electronic medical records can be especially useful in the diagnosis of pneumonia, which has a nasty habit of appearing after a patient has been hospitalized in the intensive care unit (ICU). Currently, such diagnoses are made by consensus, after a thorough chart review of the patient’s medical tests and clinical notes.
This means that a physician must comb through hand-written records and copious test results to reach the correct diagnosis—a time-consuming, resource-intensive process. Now, my colleagues and I at the University of Washington, in collaboration with Microsoft researcher Lucy Vanderwende and using Microsoft Research Splat (Statistical Parsing and Linguistic Analysis Toolkit), have created deCIPHER, a project that demonstrates the potential to use natural language processing (NLP) and machine learning to diagnose such critical illnesses automatically from the patient’s electronic medical records.
We studied the diagnosis of pneumonia in approximately 100 patients being treated in the ICU at Seattle’s Harborview Medical Center. By using the electronic medical records of these patients—whose pneumonia diagnoses had already been established by clinical consensus—we employed state-of-the-art NLP tools from Microsoft to identify the critical clinical information. We then ran that data through a machine-learning framework to see if the software could be trained to correctly diagnose the pneumonia cases based solely on an automated review of the digital medical records. The results were so promising—the software achieved a correct diagnosis with correct time-of-onset for positive cases in 84 percent of the patients—that our clinical collaborators are considering the addition of our pneumonia-detection models to the dashboard they use to monitor ICU patients.
—Meliha Yetisgen, Assistant Professor of Biomedical Informatics, University of Washington
When world-class research organizations work together on a long-term basis, the whole is greater than the sum of the parts. That premise underlies Microsoft Research’s collaborative projects and joint ventures around the globe, including our recently renewed joint research center with Inria (the French Institute for Research in Computer Science and Automation).
Since its founding in 2006, the Microsoft Research – Inria Joint Centre has innovatively applied computer science and mathematics to a host of scientific challenges, from formal methods for mathematics to distributed systems and security, computer vision and medical imaging, machine learning and big data, and social networks and privacy.
Microsoft Research – Inria includes 100 researchers overall: 40 permanent researchers from Inria, 30 permanent researchers from Microsoft Research, and 30 non-permanent researchers (interns and postdoctoral and PhD students, representing some 23 nationalities). Today, May 19, the Joint Centre continued its quest to use computing to help solve big problems, hosting an event that reported on the ambitious projects currently underway (see the list later in this blog). The event also featured the following keynotes from some of the world’s foremost computing experts, including Jeanette Wing, corporate vice president of Microsoft Research, who gave an inspiring presentation on how the joint research center is important to science, technology and society.
Jeanette Wing, corporate vice president of Microsoft Research
Georges Gonthier, principal researcher and team leader at Inria
Bertrand Thirion, director of research at the Joint Centre
The Joint Centre is currently focusing on the following projects:
Projects on formal methods and their applications
Projects on machine learning and big data
Projects on computer vision and medical imaging
Projects on social networks and privacy
All told, this one-day event captured the essence of the valuable research taking place at the Microsoft Research – Inria Joint Research Centre, and it points out the value of our long-term investments in collaborative ventures.
—Scarlet Schwiderski-Grosche, Senior Research Program Manager, Microsoft Research Connections EMEA
—Pierre-Louis Xech, Microsoft Research-Inria Joint Centre Deputy Director, Microsoft France
Chile is a long way from Microsoft Research Redmond, but its bright, inquisitive students and talented, motivated professors share our fascination in the promise of innovative software technologies. Our shared values were on clear display when representatives from Microsoft Research visited the University of Chile and the Pontifical Catholic University of Chile on May 6, 2014. Such visits enable us to check our technologies in new environments, and they always raise interesting new avenues to pursue.
Professor Sergio Ochoa was our host at the University of Chile, the country’s oldest and largest institution of higher learning, with approximately 38,000 students spread across a full range of academic divisions. The University of Chile was founded in 1842, the first in the country, and now has students in a full range of faculties and schools. We met faculty who had come from all over the world, enriching the domains and standards of the opportunities for the students.
At the University of Chile, standing, from left: Prof. Sergio Ochoa, Dr. Michal Moskal, Dr. Judith Bishop, Prof. Maria Cecilia Bastarrica, Diego Muñoz, and Prof. Alexandre Begel. Kneeling from left: Prof. Jeremy Barbay and Dr. Mircea Lungu
While there, we presented a workshop entitled, “TouchDevelop: Create Rich Mobile Cloud Apps on Your Device” to students from the computer sciences department. During the workshop, students peppered us with perceptive questions, particularly about the cloud experience that TouchDevelop offers. In explanation, Michal Moskal, a researcher at Microsoft Research, developed a chat program in TouchDevelop, showing how data can be given a “cloud” tag that makes it updateable by many users simultaneously.
The obvious follow-up question was whether TouchDevelop could also enable several programmers to work on the same code simultaneously. We believe that teamwork is very important, and we were glad to be able to announce that this capability is being built into TouchDevelop and will be released soon.
Students work on multiple platforms with TouchDevelop at the University of Chile.
At the Pontifical Catholic University of Chile, Professor Andrés Neyem organized a workshop titled, “Lab of Things – Deploying Connected Devices for Research.” At the workshop, Arjmand Samuel and Ratul Mahajan, both from Microsoft Research, talked about the Lab of Things and how this platform could be used to scale up research that relies upon connected devices and sensors. Faculty and students who were present at the workshop raised interesting questions regarding the infrastructure, network protocols, and the security and privacy of data collected as part of such research. Professor Neyem also talked about his research interests in connecting healthcare devices in homes and beyond. Specifically, he showed a demonstration of a pulse-rate monitor that is being developed in collaboration with the university’s School of Nursing, which could be deployed to about 25 homes by using the Lab of Things.
As eager as the students and faculty were at both universities, we came away just as enthused about possible links with these outstanding institutions. We look forward to working with the University of Chile to improve TouchDevelop and expand its reach, and to collaborating with the Pontifical Catholic University of Chile in deploying the Internet of Things.
—Judith Bishop, Director of Computer Science, Microsoft Research
—Arjmand Samuel, Senior Research Program Manager, Microsoft Research