Symptom

Event Type: Error
Event Source: Windows SharePoint Services 3
Event Category: (964)
Event ID: 6398
Date: <DATE>
Time: <TIME>
PM User: N/A
Computer: <SERVERNAME>
Description:
The Execute method of job definition Microsoft.Office.Server.Administration.ApplicationServerAdministrationServiceJob
(ID GUID) threw an exception. More information is included below.

Attempted to read or write protected memory. This is often an indication that other memory is corrupt.

You may also get just a blank page when you try to manage IIS

Solution/Recommendation

Check for the hotfix at http://support.microsoft.com/?id=946517

Commentary

SP1 seems to help a bit, but the hotfix closes the loop