CAUSE:- The DIV contained an UpdatePanel with the id “MultiView”. Inside the ContentTemplate of the UpdatePanel there was a asp:menu Control.- The Menu Control has these items:<Items><asp:MenuItem Text="Notes" Value="0" ></asp:MenuItem><asp:MenuItem Text="Attachment" Value="1"></asp:MenuItem><asp:MenuItem Text="Histroy" Value="2"></asp:MenuItem></Items>- Upon Clicking on any of the above three Menu items , we get “0.cells is null or not an element” .- Since the menu Control is not supported in a Partial page Update Scenario , We will not be able to make the asp:menu control work from within an UpdatePanel. WORK AROUND:The only workaround is to remove the asp:menu Control from within the ContentTemplate of the UpdatePanel.- Further reference about controls compatible with the UpdatePanel .http://www.asp.net/ajax/documentation/live/overview/UpdatePanelOverview.aspx