I ran into an issue where after deploying some custom solutions with a customer, the SSP site would not load. It would just display a message that said unexpected error. In the event logs we saw the following error.Event Type: ErrorEvent Source: Windows SharePoint Services 3Event Category: Runtime Event ID: 6610Date: 10/26/2007Time: 10:26:31 AMUser: N/AComputer: MACHINENAMEDescription:Safe mode did not start successfully. Request for the permission of type 'Microsoft.SharePoint.Security.SharePointPermission, Microsoft.SharePoint.Security, Version=220.127.116.11, Culture=neutral, PublicKeyToken=71e9bce111e9429c' failed.For more information, see Help and Support Center at http://go.microsoft.com/fwlink/events.asp.
The fix for this was to change the trust level in the web config from WSS_Minimal to WSS_Medium.
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