Occasionally different anti-virus products can interfere with SharePoint operations. The following is a list of suggested locations to exclude from your AV scanner. Remember, this is merely a suggestion, so use at your own risk!1. %PROGRAM FILES%\Common Files\Microsoft Shared\web server extensions\122. %WINNT%\temp3. %PROGRAM FILES%\Microsoft Office Server4. %WINNT%\Microsoft.NET\Framework\v2.0.50727\Temporary ASP.NET Files\5. Documents and Settings\All Users\Application Data\Microsoft\SharePoint\Config\ (the config cache)6. %WINNT%\Temp\WebTempDir
UPDATE: We've released a KB that covers this.http://support.microsoft.com/kb/952167
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The article says that certain files might have to be excluded if we are using a file-level anti-virus. We are using Nod32. is Nod32 a file-level scanner? and how can I tell if an anti-virus scans on the file level?