I wanted to put up this sample using the Feb CTP.
Basically it uses WSE 3.0 and WCF to demostrate both AnonymousCertificate configuration and MutualCertificate configuration using the service custom binding Configuration and the WSE policy file.

The point is that WSE uses MessageVersion.Soap11WSAddressingAugust2004 or MessageVersion.Soap12WSAddressingAugust2004 basically will need a custom binding for this.