If you’re working in a large solution or a project that contains numerous files, one quick way to jump to the file you want to open is to type the first few letters of the filename.  For example, if I were on filename “Class1” and wanted to select “ReadMe.txt”, I could just press Ctrl+Alt+L (in General Development Environment) to bring up Solution Explorer and then type “Rea”.  If there are no other Rea* files, ReadMe.txt will get selected.  In case of a conflict, the first filename listed wins.

I had a coworker show me this trick.  Most standard Windows list views and tree views controls support type-ahead selection, but I just never thought to try it using the Solution Explorer before.  It’s really the simple things in life =)