In the general development settings, I didn’t see this command under the Debug menu.  So, in case you want to use the keyboard to enable or disable a breakpoint, you can Ctrl+F9, which is bound to the command Debug.EnabledBreakpointNote that you won’t find a Debug.DisableBreakpoint, since this is handled by the enabled command.

Disabled breakpoint

A disabled breakpoint will still get saved in your Breakpoints window, but will be ignored while debugging.

Breakpoints window showing a disabled breakpoint

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