One of the repetitive tasks I always find myself doing for presentations and demos is adjusting the font size in VS.NET. I'll open the IDE, someone at the back of the room will announce that they can't read the font and then I'll spend a valuable 10 minutes hunting through the myriad of options for a suitable font size.
In a recent post on presentation tips, Scott Hanselman addresses this very issue. By launching devenv.exe with the /fs switch you can set all of the majority of the fonts in the IDE with one command line. For example, devenv.exe /fs 18 - will set the fonts in the IDE to 18pt. This will remain the case until you revert it back with devenv.exe /fs 8.
A great tip, I think you'll agree. You can read more of Scott's tips in his article.