http://blogs.msdn.com/b/smondal/archive/2012/08/24/signaturedescription-could-not-be-created-for-the-signature-algorithm-supplied.aspxWhile running a ClickOnce 4.5 application, you may receive the below error message: &#160; Once you click on D etails… button, it will popup the log file where you can find the below exception: Following failure messages were detected: &#160; + Exceptionen-USTelligent Evolution Platform Developer Build (Build: 5.6.50428.7875)http://blogs.msdn.com/b/smondal/archive/2012/08/24/signaturedescription-could-not-be-created-for-the-signature-algorithm-supplied.aspx#10357662Tue, 09 Oct 2012 07:46:57 GMT91d46819-8472-40ad-a661-2c78acb4018c:10357662Get Fuzzy<p>What about when this error occurs when trying to debug in VS 2012? &nbsp;Obviously .Net 4.5 is already installed. &nbsp;I&#39;m resigning my click once manifest in a post build procedure... &nbsp;Any idea how to resolve this then?</p> <div style="clear:both;"></div><img src="http://blogs.msdn.com/aggbug.aspx?PostID=10357662" width="1" height="1">http://blogs.msdn.com/b/smondal/archive/2012/08/24/signaturedescription-could-not-be-created-for-the-signature-algorithm-supplied.aspx#10355078Tue, 02 Oct 2012 12:37:48 GMT91d46819-8472-40ad-a661-2c78acb4018c:10355078Marcel<p>I&#39;m getting the same error message. I started using VS 2012 RTM with an older VS2010 .NET 4 Windows Forms project. Opened my project in VS 2012. Target Framework is still .NET 4 Framework, but the error is always thrown. I can&#39;t still believe that i have to install .NET Framework on Customers Machine to run an .NET 4 Clickonce app?!</p> <div style="clear:both;"></div><img src="http://blogs.msdn.com/aggbug.aspx?PostID=10355078" width="1" height="1">