Using SQL Server 2005 sp3, running on 32bit Vista with sp1.  I'm creating report models using Business Intelligence Development Studio and as I go to edit an expression I find that I get a message "Access to the path 'C:\Windows\system32\config' is denied."

So, I try the next logical thing and close BIDS, re-open with admin privileges (yes, like a good boy I'm still running with UAC enabled) try to edit the expression again and get the same thing.

Looking at the permissions on the folder in question, I find that my account is granted Read & Execute on the folder so I do a little more digging.

After doing a little digging on the Connect website (http://connect.microsoft.com/SQLServer/feedback/ViewFeedback.aspx?FeedbackID=334796) I find that adding "%programfiles%\Microsoft Visual Studio 8\Common7\IDE" to the Start In path of the shortcut for BIDS resolves the problem.

I find just to make my day a little easier, I tend to run BIDS elevated just to make sure when I go to deploy my reports, things go according to plan.