After my last post on implementing low-level keyboard hooks in C#, Soumitra asked if it was possible to implement a low-level mouse hook in C#, too.  Sure.  Here is an example that will print out the location of the mouse every time you press the left mouse button down:

class InterceptMouse
{
    private static LowLevelMouseProc _proc = HookCallback;
    private static IntPtr _hookID = IntPtr.Zero;

    public static void Main()
    {
        _hookID = SetHook(_proc);
        Application.Run();
        UnhookWindowsHookEx(_hookID);
    }

    private static IntPtr SetHook(LowLevelMouseProc proc)
    {
        using (Process curProcess = Process.GetCurrentProcess())
        using (ProcessModule curModule = curProcess.MainModule)
        {
            return SetWindowsHookEx(WH_MOUSE_LL, proc,
                GetModuleHandle(curModule.ModuleName), 0);
        }
    }

    private delegate IntPtr LowLevelMouseProc(int nCode, IntPtr wParam, IntPtr lParam);

    private static IntPtr HookCallback(
        int nCode, IntPtr wParam, IntPtr lParam)
    {
        if (nCode >= 0 &&
            MouseMessages.WM_LBUTTONDOWN == (MouseMessages)wParam)
        {
            MSLLHOOKSTRUCT hookStruct = (MSLLHOOKSTRUCT)Marshal.PtrToStructure(lParam, typeof(MSLLHOOKSTRUCT));
            Console.WriteLine(hookStruct.pt.x + ", " + hookStruct.pt.y);
        }
        return CallNextHookEx(_hookID, nCode, wParam, lParam);
    }

    private const int WH_MOUSE_LL = 14;

    private enum MouseMessages
    {
        WM_LBUTTONDOWN = 0x0201,
        WM_LBUTTONUP = 0x0202,
        WM_MOUSEMOVE = 0x0200,
        WM_MOUSEWHEEL = 0x020A,
        WM_RBUTTONDOWN = 0x0204,
        WM_RBUTTONUP = 0x0205
    }

    [StructLayout(LayoutKind.Sequential)]
    private struct POINT
    {
        public int x;
        public int y;
    }

    [StructLayout(LayoutKind.Sequential)]
    private struct MSLLHOOKSTRUCT
    {
        public POINT pt;
        public uint mouseData;
        public uint flags;
        public uint time;
        public IntPtr dwExtraInfo;
    }

    [DllImport("user32.dll", CharSet = CharSet.Auto, SetLastError = true)]
    private static extern IntPtr SetWindowsHookEx(int idHook,
        LowLevelMouseProc lpfn, IntPtr hMod, uint dwThreadId);

    [DllImport("user32.dll", CharSet = CharSet.Auto, SetLastError = true)]
    [return: MarshalAs(UnmanagedType.Bool)]
    private static extern bool UnhookWindowsHookEx(IntPtr hhk);

    [DllImport("user32.dll", CharSet = CharSet.Auto, SetLastError = true)]
    private static extern IntPtr CallNextHookEx(IntPtr hhk, int nCode,
        IntPtr wParam, IntPtr lParam);

    [DllImport("kernel32.dll", CharSet = CharSet.Auto, SetLastError = true)]
    private static extern IntPtr GetModuleHandle(string lpModuleName);
}