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Over the past year, I've gotten lots of questions from the ISVs I work with about how to integrate SharePoint with Silverlight. "I dunno - give it a try and let me know how it works out" quickly became a tiresome response, some I'm pleased to let you all know that we've recently announced the Silverlight Blueprint for SharePoint.
While this shouldn't be interpreted as a statement of official product direction for future releases, it's nice to have some guidance out there to help get started. The link above will point you out to http://www.ssblueprints.net/sharepoint/, which now contains:
"Six application component samples are included in the kit to get you started:
Definitely worth checking out for those so inclined.
I have the good fortune to be working on a proof of concept effort that will include these technologies, so I'll post on this more if warranted.