I've been running windows server 2008 x64 on my HP NC8430 laptop for the past week now and I have to say, its been a mixed ride (I'll leave the details to a separate blog post). One of my must-have's was to get live mesh working (which is not supported yet). After checking on the web and on some internal sites, I managed to get it working. This is not a supported scenario yet so if you want to follow these instructions please note that you're doing it at your own risk.
The main thing to note is that live mesh will not install (build # 0.9.3103.2) with UAC enabled, you will have to disable it in order to get it installed (don't worry, you will be able to re-enable it once it has been installed).
Steps to get live mesh running on Windows Server 2008 x64:
and that's it, Happy meshing!!!