A question came up from one of my victims the other day about SharePoint and how to work with it in Visual Studio 2008.  Now, whenever I have a SharePoint question, I always defer to the SharePoint guru--Phil Wheat (http://blog.austinwheats.net).  Below is his answer to the query about getting the two to work together:

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Let me recommend VS 2008 extensions for Visual Studio 2008. If you're working with content, SharePoint Designer is a great tool, but if you're working with compiled code, then you really need to be looking at Visual Studio and the things that the extensions let you do. I've got a quick link to the installer at http://blog.austinwheats.net/archive/2008/06/23/sharepoint-extensions-for-visual-studio-2008.aspx and the documentation at http://blog.austinwheats.net/archive/2008/05/12/visual-studio-extensions-for-sharepoint-developer-user-guide-released.aspx. I've also got a category on SharePoint development on my blog as well - hopefully some of it will be helpful.

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So get out there and grab some SharePoint love!