The Visual Studio 2010 and .NET Framework Beta 2 is available to MSDN subscribers on Monday, October 19th, with general availability on October 21st.

Visual Studio 2010 and .NET Framework 4 Beta 2

http://msdn.microsoft.com/en-us/vstudio/dd441784.aspx

Visual Studio 2010 and .NET Framework 4 Beta 2 Walkthroughs

http://msdn.microsoft.com/en-us/vstudio/dd441784.aspx