Peter Rip, MD Leapfrog Ventures - this guy really understands the values of composite applications / "mash ups". 

This is a fantastic piece - Lotus Symphony as a platform (sound familiar), early Ozzie (not Sabbath but our CTO), Web 2.0 and all the fun of taking a radical new approach to market.

http://earlystagevc.typepad.com/earlystagevc/2006/06/abgenial.html

Read this article then think about the possibilities that exist in the area where Dynamics CRM is the aggregator of other applications.  We provide the delivery framework and the methods to integrate previously isolated functionality.

I'm currently working with several ISVs who are doing just that.  Many industries are ripe for an aggregator of functionality within a common presentation (and familiar) framework.