http://blogs.msdn.com/commerce/archive/2009/06/15/biztalk-2006-r2.aspxTo help clarify some questions around Commerce Server BizTalk support - Commerce Server 2009 does support BizTalk 2006 R2. We are currently doing test passes against BizTalk 2009 and will advise when our test passes are completed.en-USCommunityServer 2.1 SP1 (Build: 61025.2)