The Visual Studio Hacks site has a good list of navigation shortcuts here. If you haven't read the Visual Studio Hacks book, it's worth getting.

One thing I didn't see mentioned there is using the find field to open files. If you have a project with lots of files, it can take some time to find the file in the Solution Explorer. But, you can go to the find field (control-/) and then type ">open filename". It even does autocomplete on filename.

I also like the search as you type (or whatever the feature is really called). If you hit control-I and then start typing, it will find the string as you type, so you can just type enough to get where you are going.

I also find I often use control-F3 which finds the next occurence of the selected text. I used to do the same in Mac text editors with cmd-E/cmd-G.