http://blogs.msdn.com/nishand/archive/2007/05/24/how-to-set-user-permissions.aspx1: SPSite site = null ; 2: SPWeb web = null ; 3: site = new SPSite( "http://server:100/sites/DevSite/" ); 4: web = site.OpenWeb(); 5: SPRoleAssignment roleAssignment = new SPRoleAssignment( "domain\\user" , "alias@domain.com" , "Nishand" , "Simple Testen-USCommunityServer 2.1 SP1 (Build: 61025.2)