I just saw two folks with an issue installing VS or Express because they had Kaspersky AntiVirus installed.

The error you see int he setup log is:

[11/07/05, 19:11:01] setup.exe: [2] ISetupModule::SetManager() failed in ISetupManager::LoadSetupObjectGuid() : vs_setup.dll

If that product is installed, it will hang the VS installation.

Work around is to uninstall the anti-virus before installing VS.  Note - just disabling it is not enough.

For more info, check out the forum post at: http://forums.microsoft.com/MSDN/ShowPost.aspx?PostID=126688&SiteID=1