Download Research Tools
Every discipline has its own language. The ability to communicate and collaborate in a discipline-specific language is essential to scientific research, especially in an environment characterized by staggering volumes of data.
In chemistry, not only is there a specific language, but also specific symbols. Empowering those symbols by enabling them to communicate across technologies and formats, as well as simplifying authoring and semantic annotation, is at the heart of the Chemistry Add-in for Word. Informally called Chem4Word, this free tool is being unveiled today during the American Chemical Society’s Spring 2010 National Meeting & Exposition.
Chem4Word makes it easier for students, chemists and researchers to insert and modify chemical information, such as labels, formulas and 2-D depictions, from within Microsoft Office Word. Designed for and tested on both Word 2007 and Word 2010, it harnesses the power of Chemical Markup Language (XML for chemistry), making it possible not only to author chemical content in Word, but also to include the data behind those structures. Chem4Word and Chemical Markup Language make chemistry documents open, readable and easily accessible, not just to other humans, but also to other technologies.
In the image below, the name and 2D views of the same chemical are shown in the document, along with the Chemistry Navigator, which displays all of the chemistry zones within the current document.
In addition to authoring functionality, Chem4Word enables user denotation of inline “chemical zones,” the rendering of high-quality and print-ready visual depictions of chemical structures and the ability to store and expose semantic-rich chemical information across the global chemistry community.
The product of an ongoing collaboration between Microsoft Research and Dr. Peter Murray-Rust, Dr. Joe Townsend, and Jim Downing from the Unilever Centre for Molecular Science Informatics at the University of Cambridge, the Chem4Word project took inspiration from the mathematic-equation authoring capabilities in Word 2007. We also have taken advantage of user-interface extensibility and XML features already included in Office 2007 and Office 2010, and we hope this provides a demonstration of the power of Microsoft Office as a platform. Microsoft Research worked closely with key individuals in the field of chemistry to develop this tool, but Microsoft Office provides the tools and resources to enable other domains to develop on top of Office applications.
Further guiding the development of the Chem4Word project was the Microsoft External Research team’s commitment to supporting the scholarly communications lifecycle, which calls for software and related services that enable the coordinated, seamless exchange of data and information, from authoring through publication to long-term preservation.
The beta release of the Chemistry Add-in for Word is available for free download. Later this year, it will be released as an open-source project under an Apache license via CodePlex.
Alex Wade, director for Scholarly Communication, Microsoft Research
Human trafficking of minors—including the illegal trade of children and teens for commercial sexual exploitation—is a crime so vile that it makes most people shudder. But unfortunately, not everyone recoils: pedophiles and procurers have made the commercial sexual exploitation of children an international business, and there is little doubt that technology is increasingly playing a role in their criminal practices. Which is why today I am pleased to announce that Microsoft Research Connections is partnering with danah boyd, one of the top social media researchers from the Microsoft New England Research and Development Lab, and the Microsoft Digital Crimes Unit to issue a Request for Proposals (RFP) to investigate the implications of technology in this heinous crime.
According to Shared Hope International, at least 100,000 juveniles are the victims of child sex exploitation in the United States each year. (photo courtesy of iStockphoto)
Technology is a tool, and like any tool, it can be put to good or evil purposes. Currently, there is a paucity of information regarding technology’s role in human trafficking. We don’t know if there are more human trafficking victims as a result of technology, nor do we know if law enforcement can identify perpetrators more readily from the digital traces that they leave. One thing that we do know is that technology makes many aspects of human trafficking more visible and more traceable, for better and for worse. Yet focusing on whether technology is good or bad misses the point; it is here to stay, and it is imperative that we understand its part in human trafficking. More importantly, we need to develop innovative ways of using technology to address the horrors of this crime.
Over the last several months, I have spent significant time talking with organizations, victims, and researchers who are working on this problem. It has become a passion for me, in part because at age 14 I ran away from home. I was put in a group home, then into foster care, and finally emancipated. Back then, I was fortunate that no one targeted me or trapped me into the human trade; living on the street and working in the human trade never crossed my mind. And luckily, I found teachers who helped me understand my potential and the opportunities available to me. Now, in partnership with the anti-trafficking community, I want to do all I can to develop innovative ways of using technology to combat human trafficking and help minors in the United States understand there are other options.
To do so, we must untangle technology’s role in different aspects of the human trafficking ecosystem. This is our hope with this RFP, and we look forward to hearing your responses.
—Rane Johnson, Director of Education and Scholarly Communication, Microsoft Research Connections
Millions of people worldwide live with type 1 diabetes, a potentially devastating disease with no known cure. People who have type 1 diabetes do not produce insulin in their pancreas, so they must constantly monitor their blood sugar levels while balancing food intake against insulin intake. It’s a mentally taxing, painful process that must be repeated throughout the day.
A collaboration between Associate Professor Babak Parviz at the University of Washington (UW) and Microsoft Senior Researcher Desney Tan is focused on developing a non-invasive, technological solution that promises to improve both the health and overall quality of life for people with diabetes: a contact lens that monitors blood glucose levels. The functional lens technology is representative of a trend in technology known as Natural User Interface (NUI).
NUI technology has the potential to provide user benefits without being obvious to others or intrusive to the user. We believe it has tremendous potential in the healthcare industry, where technology is a necessary, but not always pleasant, part of a patient’s diagnosis or care. The functional contact lens is an excellent example of how NUI can change patient monitoring from “snapshots” of information to continuous health monitoring that could potentially improve the wearer’s overall health—especially for those with a chronic disease, such as diabetes.
Today, people with type 1 diabetes use needles to draw blood from their fingers multiple times throughout the day—every day, including meal times—to check their blood glucose levels. By monitoring their glucose levels, they can more easily ensure that they maintain an acceptable glucose level, which is critical to optimal health and longevity for diabetes patients.
The Daily Impact of Diabetes
Daily, repeated blood draws are a painful necessity for people with diabetes. This process has limitations because the monitoring is only periodic. Diabetics may experience glucose fluctuations that require correction—for example, by increasing insulin intake or eating a piece of candy to raise their blood sugar level—anytime of the day. Regular glucose monitoring, in addition to sensible dietary choices, are part of daily life for Kevin McFeely, who was diagnosed with type 1 diabetes 30 years ago, and his two young children, who also have diabetes.
“If I don’t check my blood sugar, or my children don’t check their blood sugar daily, there are some different things that could potentially happen,” he explained. “If my blood sugar gets too high, I have noticed that my vision begins to blur, I begin feeling nauseous, very, very tired, and just almost physically sick. And potentially, if I let that go, I could pass out from having high blood glucose.”
Low blood sugar also presents a danger to people with diabetes. If glucose falls too low, a diabetic may begin to sweat, suffer an elevated heart rate, and potentially lose consciousness. So it is critical that diabetics monitor their blood glucose on a regular basis throughout the day. McFeely’s children, who are ages seven and ten, are responsible for managing their disease and monitoring themselves at school throughout the day.
“I’m used to testing myself six to eight times per day. I’ve been doing it for 30 years,” McFeely says. “But boy, when I think about my children… I mean, you have a spring-loaded needle that’s coming into your finger, and it hurts them. I can see their faces [when they test], and I can see them cringe.”
A New Approach to Monitoring Health
As envisioned, the lens would be worn daily, just like regular contact lenses. But instead of, or in addition to, correcting vision, the lens would monitor the wearer’s glucose level through their tears. Much of the information that can be obtained through blood testing is also accessible on the surface of the eye. The functional lens is being designed to sample eye fluid, analyze it, and transmit the information to a reporting machine. A tiny radio transmitter embedded in the lens will handle the information transfer.
Parviz’s team at UW has built a variety of contact lenses with small radios and antennas built in, enabling them to draw power as well as send and receive information through radio frequencies. Also, the UW team has been able to place a glucose sensor on the contact lens and demonstrate that it can detect glucose at levels that are found in the tear film. The goal is to unite these elements to develop a contact lens that constantly monitors the blood glucose level and records information that can be accessed later by the patient’s doctor.
McFeely is hopeful that technology, like the functional contact lens, can improve the monitoring and care options available to his children. “Thinking about the functional contact lens for my children who are both type 1 diabetic—I think that would be incredible,” he said. “Given that my children are diagnosed at such a young age, it does have the potential to help them live a longer, healthier life.”
Visualizing Future Applications
Ideally, the lens will do more than just record information. The UW team envisions a way to automatically display important information—including abnormal glucose or insulin alerts—in the lens wearer’s view. It could alert the wearer when they should stop eating due to glucose levels, or remind them when it’s time to get a snack. This real-time feedback would empower the user to react quickly, avoiding health-threatening or uncomfortable episodes. The visual information would be dormant the rest of the time, adhering to the NUI idea of being unobtrusive until needed.
Once fully developed, the technology could be used to replace virtually any screening or diagnostics that currently depend upon blood draws. Additionally, the researchers who are involved in the project envision a future in which contact lenses deliver medicine directly into the bloodstream through the cornea.
—Kristin Tolle, Director, Natural User Interface, Microsoft Research Connections